FWIW - I just downloaded [PlayOnMac](https://www.playonmac.com/en), downloaded the Windows GW2 installer, and ran through PlayOnMac.
Once it reached the "playable" point in the download, I went into the game and ran around. So it seems to work at some level. Fonts look a bit wonky, but that could be a not-yet-downloaded thing, a setting, or just the way they look on Windows. Still totally readable and usable.
This will be a better solution than virtualization since PlayOnMac uses [WINE](https://www.winehq.org/) which is more like a Windows compatibility layer, so it won't affect speed as much.